Our Technology

SpectraDigital Corporation (SDC) has developed an in vitro diagnostic (IVD) device, HIV SpectraPoint, to determine the efficacy of antiviral cocktails for a specific patient with acquired immunodeficiency syndrome (AIDS). Our results indicate that this method provides information related to the efficacy of the anti-virals and another tool to make informed decisions in the treatment of AIDS patients. This information may be equally useful to the currently used HIV Drug Resistance Genotype/Phenotype Assays used in economically developed countries. The advantage of our approach is that it can provide an assessment of the most efficacious cocktail within several hours and at a considerably lower cost than existing methods. The system is highly portable and does not require complex installation or training for use.

Light scattering is a phenomenon that occurs when light, passing through a media with particles, interacts with the particles. A scattering particle can be defined if it has any bounded region of refractive index variation. The study of light scattered from particles in a suspension has provided information on the size distribution, shape, molecular weight, and, internal structure changes.

More recently, the application of light scattering techniques to biological cells has been possible due to the availability of low-cost laser sources coupled with very sensitive optical detectors. The measurement of light scattering from suspensions of biological cells can be used to infer physiological information about the cells without the need for extra reagents, such as fluorescence contrast agents. SDC has considerable experience in the application of light scattering methods to obtain information about physiological processes through the use of proprietary algorithms.

 


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This page was last updated August 1st, 2006.